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Cocaine eye drops are regularly utilized by neurologists when analyzing sufferers suspected of having Horner syndrome. In Horner syndrome, sympathetic innervation to the attention is blocked. In the wholesome eye, cocaine will stimulate the sympathetic nerves by inhibiting norepinephrine reuptake, and the pupil will dilate; if the individual has Horner syndrome, the sympathetic nerves are blocked, as well as the affected eye will continue being constricted or dilate into a lesser extent compared to the opposing (unaffected) eye which also receives the eye drop examination. If equally eyes dilate equally, the individual does not have Horner syndrome.[39]
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